Multimedia
Dendritic cell antigen animation
Dendritic cells capture foreign material, process it and pass it to naïve T cells to initiate immune responses. Cytotoxic T cells then seek out and destroy cells expressing the antigen, while helper T cells stimulate B cells to produce antibodies.
Whether derived from myeloid or lymphoid lineages, mature dendritic cells carry out their function through interactions with major histocompatibility complex (MHC) molecules. There are two types of MHC: class I and class II and, therefore, two pathways of dendritic cell antigen presentation. The animation provides a simple overview of each pathway.
View Animation (Flash, ca. 11 min)
Regulatory T cell animation
Tregs are a major area of therapeutic interest as their pathways of action may be manipulated to prevent autoimmune diseases and transplant rejection.
Our interactive animation is both educational and practical. It overviews Treg function and is easy to navigate, providing links to journal abstracts and our full Treg antibody range.
View Animation (Flash, interactive)
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Discussion & Comments Board
Regulatory T cell animation
DL, UK
I have been asked to measure naturally occuring Tregs in rat blood using only Cd4CD25. Is this a sound approach or must we add FoxP3? Also in ‘nomral’ rats what is the frequency of natural Tregs as this will infleucne the number vents needed to detect changes in their levels.
Respond
T, Vietnam
Thank you for your Treg animation. I still have some complex. First, IL-2 can combine with CD25 (IL-2 receptor), so can deplete Tregs, but in some research, they said that IL-2 boots human Treg function in vivo. And what is the Antigen specificity of Tregs? More information can help us to reach the best application of immuntherapies in cancer treatment. Thank you
Respond
LV, Spain
A clear , fully didactic and very comprensibely presentation for helping to understand and is quit difficult to see on books.
SMH, Tunisia
Special thanks for the ab teamI am a tunisian research worker in the immunohaematology domain.I would like to receive a copy from this movie if it is possible.
AN, Colombia-South America
This is a excellent animation to learn and understand the basic function mechanisms of regulatory T cells. Would be great if the animation had sound.
M, France
it’s a very good and informatory animation. But i have a questionwhy tregs suppress ongoing immune response when there is antigen in the body or inother words when immune system is activated tregs should not stop or supress the immune response.
TPS, Austria
I think Treg cell could be a future weapon for autoimmune diseases and cancer.”BULLET FOR BAD CELLS”
MF, Pakistan
Hi,i was too very happy to see your hardworking in the field of immunology. What i think now realy you have done too much good and i wish you go still forward in this field. I m student of microbiology.
NK, USA
I was very impressed with the animation and details. I found your site from a paper discussing CD39 as a Treg marker so suggest adding it to your figure (and making an antibody to the murine Ab).
